欧盟重新评估木松香甘油酯作为食品添加剂的安全性

食品伙伴网 2023-07-27 16:25:41


(相关资料图)

    2023年7月19日,据欧盟食品安全局(EFSA)消息,欧盟食品添加剂和调味剂小组(FAF)重新评估了木松香甘油酯(neohesperidine dihydrochalcone)(E 445)作为食品添加剂的安全性。

经过评估,小组得出结论,无论是在最大允许水平上,还是在报告的用途和使用水平下,使用木松香甘油酯(E 445)都不会引起安全问题。部分原文报道如下:

Glycerol esters of wood rosin (GEWR) (E 445) were re-evaluated in 2018. On the toxicity database and given the absence of reproductive and developmental toxicity data, the acceptable daily intake (ADI) of 12.5 mg/kg body weight (bw) per day for GEWR (E 445) established by the Scientific Committee on Food (SCF) in 1994 was considered temporary. The conclusions of the assessment were restricted to GEWR derived from Pinus palustris and Pinus elliottii and with a chemical composition in compliance with GEWR used in the toxicological testing. Following a European Commission call for data to submit data to fill the data gaps, the present follow-up opinion assesses data provided by interested business operators (IBOs). Considering the technical data submitted by IBOs, the EFSA Panel on Food Additives and Flavourings (FAF Panel) recommended some modifications of the existing EU specifications for E 445, mainly a revision of the definition of the food additive and lowering the limits for toxic elements. Considering the available toxicological database evaluated during the re-evaluation of E 445 by the ANS Panel in 2018, and the toxicological studies submitted by the IBOs, the Panel established an ADI of 10 mg/kg bw per day based on the no observed adverse effect level (NOAEL) of 976 mg/kg bw per day from the newly available dietary reproduction/developmental toxicity screening study in rats and applying an uncertainty factor of 100. Since GEWR from P. palustris and P. elliottii were tested in the toxicity studies considered to establish the ADI and in the absence of detailed information on the chemical composition (major constituents) in GEWR generated from other Pinus species, thus not allowing read across, the ADI is restricted to the GEWR (E 445) manufactured from P. palustris and P. elliottii. The Panel concluded that there was no safety concern for the use of GEWR (E 445), at either the maximum permitted levels or at the reported uses and use levels.

x

热门推荐

欧盟重新评估木松香甘油酯作为食品添加剂的安全性

2023-07

雷蛇推出 Xanthus 系列背包,雷蛇绿经典亮眼

2023-07

中国广核:7月11日融资买入1879.46万元,融资融券余额2.44亿元

2023-07

首批智慧电梯将在沪落地

2023-07

金地集团于深圳参设科技公司,含AI软件开发业务

2023-07

文创雪糕风还能刮多久

2023-07

世界最佳自然保护地!安徽一地入选

2023-07

模拟驾驶训练什么时候出 公测上线时间预告

2023-07

暑期档票房破70亿元 研报称电影行业呈现明显的复苏态势

2023-07

当代马来西亚人物画名家邀请展在吉隆坡开幕

2023-07

推荐阅读

深圳发布养老服务合同示范文本规范养老机构服务行为

2022-03

山东深耕文化资源 推动旅游业高质量发展

2021-12

安徽潜山两车相撞 已致8人死亡3人受伤

2021-12

56位残疾人士登上黄山 互利互勉共建生活希望

2021-12

山西忻州古城:一城风华延续千年历史文脉

2021-12

上海洋山海关首次在出口货运渠道查获夹带卷烟

2021-12

西藏林芝:多彩民俗活动迎接工布新年

2021-12

呼伦贝尔新巴尔虎右旗公布1例无症状感染者行动轨迹

2021-12

新增“53+1” 内蒙古累计本土确诊病例增至185例

2021-12

面对儿童不得不防的“杀手”,这把椅子很重要!

2021-12